Progesterone and Other Female Hormones: Functions and Effects

La progesterona

Let’s talk about the hormones responsible for our menstrual cycle, our ability to get pregnant, our sex drive, and basically every function that makes our bodies work the way they do: progesterone and the other female hormones.

Female hormones control everything — from mood, motivation and physiological needs, to making sure the body runs the way it should.

To understand how our body’s chemistry works (which has some clear differences from men’s), let’s break down how hormones actually function.

What is progesterone?

Progesterone is a female sex hormone responsible for creating the right conditions for fertilization. It prepares the endometrium during the menstrual cycle to receive a possible pregnancy, and if that happens, it helps the pregnancy progress normally.

This hormone is produced by the ovaries in the corpus luteum (a structure formed after ovulation), and later by the placenta.

How does it work?

Progesterone is the hormone that keeps the body from treating a fertilized egg as a threat at the start of pregnancy, helps maintain the pregnancy, and ultimately triggers labor at the end of it.

It’s also responsible for lactation and for the increase in bra size during pregnancy, since it prepares the mammary glands to produce breast milk.

When fertilization doesn’t happen, the excess progesterone that thickened the endometrium during the rest of the cycle is shed through menstruation.

How do this hormone’s levels affect the body?

  • Our body temperature rises by about half a degree around ovulation, and metabolism speeds up — appetite and energy levels increase. These are the days of decision-making and feeling fully empowered.
  • During pregnancy, with rising progesterone, hair and skin often hit their best phase. This hormone lowers levels of male hormones, which makes hair grow faster.
  • Some research suggests this hormone affects not just the reproductive organs but also receptors in the brain — which is why it has antidepressant effects.

Other female hormones, and what they do

Estrogens

Estrogen molecule
Estrogen

Along with progesterone, estrogens are the other major female sex hormones. Derived from androgens (male hormones), there are three main estrogens in the body: estrone, estradiol and estriol.

Estrogens serve several functions and are basically responsible for our feminine shape.

  • They influence how fat is distributed around the body. With puberty, fat starts accumulating around the hips and breasts, giving us the typical female silhouette.
  • A drop in this hormone is what causes mood swings: depression, anxiety and irritability.
  • It prevents bone softening and porosity.
  • It plays a role in fat and cholesterol metabolism.

Estrogen levels rise mainly during the first 7 days of the menstrual cycle.

Testosterone

Biochemical structure of testosterone
Biochemical structure of testosterone

Yes, it’s one of the female hormones too — even though you might associate it with masculinity, women have it as well, just in smaller amounts than men. It’s the hormone mainly responsible for sex drive. It also contributes to competitiveness and physical energy, and helps reduce fat storage.

When testosterone levels drop, sex drive tends to decrease and weight tends to increase.

DHEA

Biochemical structure of DHEA
Biochemical structure of DHEA

DHEA is a hormone produced by the adrenal glands, which are also responsible for producing other hormones like testosterone and estrogen. It’s closely tied to aging, since its levels decline over the years.

That’s why there are so many supplements, creams and pills aimed at slowing down visible signs of aging and improving cognitive function and body composition.

Oxytocin

Biochemical structure of oxytocin, the love hormone
Biochemical structure of oxytocin

The hormone of happiness, pleasure and love. It’s present in both men and women and is released by the brain. In women, it heightens sexual pleasure, triggers orgasm and supports well-being during breastfeeding. Because it also has a relaxing effect, it can help ease period cramp symptoms.

The body works as the interconnected system it is. Many other hormones play a role in normal female processes too, including thyroid hormones, cortisol, and others.

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Foods that help balance your hormones

When female hormones fall out of balance, the body tends to show it: loss of sex drive, weight loss or gain, hair loss, or other issues that can affect your health.

It largely comes down to diet. If you’re confident these symptoms aren’t linked to an underlying condition but to small hormonal dips or spikes, certain foods can help bring your hormones back into balance:

  • Salmon, sardines or any fatty fish: omega-3s, with all their benefits as high-quality fats, help raise progesterone levels.
  • Likewise, vitamin B6, found in grains, legumes and nuts, supports the formation of the corpus luteum, which is responsible for releasing progesterone.
  • Broccoli is a good source of zinc, calcium and vitamin B, which helps raise testosterone levels.
  • Soy, flaxseed, spinach and other legumes contain natural estrogens that can help ease period cramps and perimenopause symptoms. They’re excellent natural regulators for these hormones.
Gynecology consultation
A gynecology consultation

When to see a doctor

Whenever you notice unusual symptoms — like missing your period for more than three months, concerning signs during pregnancy, excessive menstrual pain, or other signals that something isn’t right — see your doctor.

Other signs that could point to a hormonal disorder include excess hair growth where it shouldn’t be (like around the nipples), or hair loss.

Hormonal deficiency in the early weeks of pregnancy is one of the causes of miscarriage. However, a doctor can treat this with progesterone injections to help prevent it.

The same may be prescribed for irregular menstrual cycles. Similarly, in cases involving polycystic ovary syndrome or other conditions, birth control pills are a common treatment.

If in doubt, the best move is never to self-medicate — see a specialist who can help you get to the bottom of it and start feeling better.

What is the main function of progesterone?

Progesterone prepares the endometrium to receive a fertilized egg, helps maintain pregnancy once it occurs, and triggers labor at full term. When there’s no pregnancy, the excess builds up in the endometrium and is shed as your period.

What female hormones affect mood the most?

Estrogen and progesterone are the main drivers of mood swings during the cycle. Falling estrogen is linked to irritability and low mood, while rising progesterone around ovulation is linked to more energy and a more antidepressant effect.

Can diet really help balance hormones?

Yes, when the imbalance is mild and not caused by an underlying condition. Fatty fish (omega-3), vitamin B6 from grains and nuts, zinc-rich foods like broccoli, and natural phytoestrogens from soy and flaxseed can all help support hormonal balance.

When should I see a doctor about a hormonal issue?

See a doctor if your period stops for more than three months, if you notice unusual signs during pregnancy, excessive menstrual pain, unexpected hair growth, or hair loss. Don’t self-medicate — a specialist can identify the cause and the right treatment.

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